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Long term usage of dexamethasone accelerating the initiation of osteoarthritis via enhancing the extracellular matrix calcification and apoptosis of chondrocytes

Systemic application of glucocorticoids is an essential anti-inflammatory and immune-modulating therapy for severe inflammatory or autoimmunity conditions. However, its long-term effects on articular cartilage of patients' health need to be further investigated. In this study, we studied the ef...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Ni, Zhenhong, Huang, Junlan, Zhang, Ruobin, Zhang, Jinfan, Zhang, Bin, Kuang, Liang, Sun, Xianding, Zhang, Dali, Su, Nan, Qi, Huabing, Yang, Jing, Jin, Min, Luo, Fengtao, Chen, Hangang, Zhou, Siru, Du, Xiaolan, Ouyang, Junjie, Wang, Zuqiang, Xie, Yangli, Tan, Qiaoyan, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579451/
https://www.ncbi.nlm.nih.gov/pubmed/34803488
http://dx.doi.org/10.7150/ijbs.64152