Cargando…
Long term usage of dexamethasone accelerating the initiation of osteoarthritis via enhancing the extracellular matrix calcification and apoptosis of chondrocytes
Systemic application of glucocorticoids is an essential anti-inflammatory and immune-modulating therapy for severe inflammatory or autoimmunity conditions. However, its long-term effects on articular cartilage of patients' health need to be further investigated. In this study, we studied the ef...
Autores principales: | Chen, Liang, Ni, Zhenhong, Huang, Junlan, Zhang, Ruobin, Zhang, Jinfan, Zhang, Bin, Kuang, Liang, Sun, Xianding, Zhang, Dali, Su, Nan, Qi, Huabing, Yang, Jing, Jin, Min, Luo, Fengtao, Chen, Hangang, Zhou, Siru, Du, Xiaolan, Ouyang, Junjie, Wang, Zuqiang, Xie, Yangli, Tan, Qiaoyan, Chen, Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579451/ https://www.ncbi.nlm.nih.gov/pubmed/34803488 http://dx.doi.org/10.7150/ijbs.64152 |
Ejemplares similares
-
Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice
por: Zhou, Siru, et al.
Publicado: (2016) -
Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway
por: Zhang, Dali, et al.
Publicado: (2021) -
Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling
por: Sun, Xianding, et al.
Publicado: (2020) -
Inhibition of aberrant Hif1α activation delays intervertebral disc degeneration in adult mice
por: Wang, Zuqiang, et al.
Publicado: (2022) -
Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL‐1β/NF‐κB pathway
por: Wang, Zuqiang, et al.
Publicado: (2017)