Systemic Deficiency of GHR in Pigs leads to Hepatic Steatosis via Negative Regulation of AHR Signaling

Laron syndrome (LS) is an autosomal recessive genetic disease mainly caused by mutations in the human growth hormone receptor (GHR) gene. Previous studies have focused on Ghr mutant mice, but compared with LS patients, Ghr knockout (KO) mice exhibit differential lipid metabolism. To elucidate the re...

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Detalles Bibliográficos
Autores principales: Han, Qi, Chen, Huiling, Wang, Likai, An, Yang, Hu, Xiaoxiang, Zhao, Yaofeng, Zhang, Hao, Zhang, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579453/
https://www.ncbi.nlm.nih.gov/pubmed/34803486
http://dx.doi.org/10.7150/ijbs.64894

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