Cullin3 deficiency shapes tumor microenvironment and promotes cholangiocarcinoma in liver-specific Smad4/Pten mutant mice

Cholangiocarcinoma (CC), the most lethal type of liver cancer, remains very difficult to treat due to an incomplete understanding of the cancer initiation and progression mechanisms and no effective therapeutic drugs. Thus, identification of genomic drivers and delineation of the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Quan, Yingyao, Zeng, Jianming, Lyu, Xueying, Wang, Haitao, Lei, Josh Haipeng, Feng, Yangyang, Xu, Jun, Chen, Qiang, Sun, Heng, Xu, Xiaoling, Lu, Ligong, Deng, Chu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579464/
https://www.ncbi.nlm.nih.gov/pubmed/34803491
http://dx.doi.org/10.7150/ijbs.67379

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