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Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study

BACKGROUND: Home delivery has been associated with mother-to-child transmission of HIV and remains high among HIV-infected women. Predictors for home delivery in the context of HIV have not been fully studied and understood in Northern Uganda. We therefore aimed to find out the incidence and risk fa...

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Autores principales: Kasede, Agnes Napyo, Tylleskär, Thorkild, Mukunya, David, Tumuhamye, Josephine, Ndeezi, Grace, Arach, Anna Agnes Ojok, Waako, Paul, Tumwine, James K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579617/
https://www.ncbi.nlm.nih.gov/pubmed/34758766
http://dx.doi.org/10.1186/s12884-021-04222-5
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author Kasede, Agnes Napyo
Tylleskär, Thorkild
Mukunya, David
Tumuhamye, Josephine
Ndeezi, Grace
Arach, Anna Agnes Ojok
Waako, Paul
Tumwine, James K.
author_facet Kasede, Agnes Napyo
Tylleskär, Thorkild
Mukunya, David
Tumuhamye, Josephine
Ndeezi, Grace
Arach, Anna Agnes Ojok
Waako, Paul
Tumwine, James K.
author_sort Kasede, Agnes Napyo
collection PubMed
description BACKGROUND: Home delivery has been associated with mother-to-child transmission of HIV and remains high among HIV-infected women. Predictors for home delivery in the context of HIV have not been fully studied and understood in Northern Uganda. We therefore aimed to find out the incidence and risk factors for home delivery among women living with HIV in Lira, Northern Uganda. METHODS: This prospective cohort study was conducted between August 2018 and January 2020 in Lira district, Northern Uganda. A total of 505 HIV infected women receiving antenatal care at Lira regional referral hospital were enrolled consecutively and followed up at delivery. We used a structured questionnaire to obtain data on exposures which included: socio-demographic, reproductive-related and HIV-related characteristics. Data was analysed using Stata version 14.0 (StataCorp, College Station, Texas, U.S.A.). We estimated adjusted risk ratios using Poisson regression models to ascertain risk factors for the outcome of interest which was home delivery (which is delivering an infant outside a health facility setting under the supervision of a non-health worker). RESULTS: The incidence of home delivery among women living with HIV was 6.9% (95%CI: 4.9–9.5%). Single women were more likely to deliver at home (adjusted risk ratio = 4.27, 95%CI: 1.66–11). Women whose labour started in the night (night time onset of labour ARR = 0.39, 95%CI: 0.18–0.86) and those that were adherent to their ART (ARR = 0.33, 95%CI: 0.13–0.86) were less likely to deliver at home. CONCLUSION: Home delivery remains high among women living with HIV especially those that do not have a partner. We recommend intensified counselling on birth planning and preparedness in the context of HIV and PMTCT especially for women who are: separated, divorced, widowed or never married and those that are not adherent to their ART. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-021-04222-5.
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spelling pubmed-85796172021-11-10 Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study Kasede, Agnes Napyo Tylleskär, Thorkild Mukunya, David Tumuhamye, Josephine Ndeezi, Grace Arach, Anna Agnes Ojok Waako, Paul Tumwine, James K. BMC Pregnancy Childbirth Research BACKGROUND: Home delivery has been associated with mother-to-child transmission of HIV and remains high among HIV-infected women. Predictors for home delivery in the context of HIV have not been fully studied and understood in Northern Uganda. We therefore aimed to find out the incidence and risk factors for home delivery among women living with HIV in Lira, Northern Uganda. METHODS: This prospective cohort study was conducted between August 2018 and January 2020 in Lira district, Northern Uganda. A total of 505 HIV infected women receiving antenatal care at Lira regional referral hospital were enrolled consecutively and followed up at delivery. We used a structured questionnaire to obtain data on exposures which included: socio-demographic, reproductive-related and HIV-related characteristics. Data was analysed using Stata version 14.0 (StataCorp, College Station, Texas, U.S.A.). We estimated adjusted risk ratios using Poisson regression models to ascertain risk factors for the outcome of interest which was home delivery (which is delivering an infant outside a health facility setting under the supervision of a non-health worker). RESULTS: The incidence of home delivery among women living with HIV was 6.9% (95%CI: 4.9–9.5%). Single women were more likely to deliver at home (adjusted risk ratio = 4.27, 95%CI: 1.66–11). Women whose labour started in the night (night time onset of labour ARR = 0.39, 95%CI: 0.18–0.86) and those that were adherent to their ART (ARR = 0.33, 95%CI: 0.13–0.86) were less likely to deliver at home. CONCLUSION: Home delivery remains high among women living with HIV especially those that do not have a partner. We recommend intensified counselling on birth planning and preparedness in the context of HIV and PMTCT especially for women who are: separated, divorced, widowed or never married and those that are not adherent to their ART. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-021-04222-5. BioMed Central 2021-11-10 /pmc/articles/PMC8579617/ /pubmed/34758766 http://dx.doi.org/10.1186/s12884-021-04222-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Kasede, Agnes Napyo
Tylleskär, Thorkild
Mukunya, David
Tumuhamye, Josephine
Ndeezi, Grace
Arach, Anna Agnes Ojok
Waako, Paul
Tumwine, James K.
Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study
title Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study
title_full Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study
title_fullStr Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study
title_full_unstemmed Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study
title_short Incidence of home delivery among women living with HIV in Lira, Northern Uganda: a prospective cohort study
title_sort incidence of home delivery among women living with hiv in lira, northern uganda: a prospective cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579617/
https://www.ncbi.nlm.nih.gov/pubmed/34758766
http://dx.doi.org/10.1186/s12884-021-04222-5
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