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Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells
BACKGROUND: A new strategy, particularly a novel combination, for immunotherapy in microsatellite stable metastatic colorectal cancer (mCRC) treatment needs to be formulated. Studies on the interferon-γ (IFN-γ)/ Janus kinase (JAK)/ signal transducer and activator of transcription (STAT)1 pathway pro...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579664/ https://www.ncbi.nlm.nih.gov/pubmed/34758826 http://dx.doi.org/10.1186/s12929-021-00769-9 |