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Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells

BACKGROUND: A new strategy, particularly a novel combination, for immunotherapy in microsatellite stable metastatic colorectal cancer (mCRC) treatment needs to be formulated. Studies on the interferon-γ (IFN-γ)/ Janus kinase (JAK)/ signal transducer and activator of transcription (STAT)1 pathway pro...

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Detalles Bibliográficos
Autores principales: Liang, Yi-Hsin, Chen, Kuo-Hsing, Tsai, Jia-Huei, Cheng, Yung-Ming, Lee, Chang-Cheng, Kao, Chiu-Hwa, Chan, Kuang-Yu, Chen, Yeh-Ting, Hsu, Wen-Ling, Yeh, Kun-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579664/
https://www.ncbi.nlm.nih.gov/pubmed/34758826
http://dx.doi.org/10.1186/s12929-021-00769-9

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