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Mapping Electromechanical Coupling Pathways in Voltage-Gated Ion Channels: Challenges and the Way Forward

Inter- and intra-molecular allosteric interactions underpin regulation of activity in a variety of biological macromolecules. In the voltage-gated ion channel superfamily, the conformational state of the voltage-sensing domain regulates the activity of the pore domain via such long-range allosteric...

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Detalles Bibliográficos
Autores principales: Cowgill, John, Chanda, Baron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579740/
https://www.ncbi.nlm.nih.gov/pubmed/34139217
http://dx.doi.org/10.1016/j.jmb.2021.167104