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Intracellular Low Iron Exerts Anti-BK Polyomavirus Effect by Inhibiting the Protein Synthesis of Exogenous Genes

BK polyomavirus (BKPyV) is a small double-stranded DNA virus and ubiquitous human pathogen that particularly affects immunocompromised individuals. Antiviral therapy for BKPyV is urgently needed. Intracellular irons have an important role in many viral infections, yet its contribution to BKPyV and r...

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Detalles Bibliográficos
Autores principales: Sun, Jiajia, Shi, Yejing, Shi, Huichun, Hou, Yumin, Hu, Chunlan, Zeng, Yigang, Wu, Guoyi, Zhu, Tongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579847/
https://www.ncbi.nlm.nih.gov/pubmed/34756078
http://dx.doi.org/10.1128/Spectrum.01094-21