A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps

RNA viruses replicate as complex mutant spectra termed viral quasispecies. The frequency of each individual genome in a mutant spectrum depends on its rate of generation and its relative fitness in the replicating population ensemble. The advent of deep sequencing methodologies allows for the first-...

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Detalles Bibliográficos
Autores principales: Delgado, Soledad, Perales, Celia, García-Crespo, Carlos, Soria, María Eugenia, Gallego, Isabel, de Ávila, Ana Isabel, Martínez-González, Brenda, Vázquez-Sirvent, Lucía, López-Galíndez, Cecilio, Morán, Federico, Domingo, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579923/
https://www.ncbi.nlm.nih.gov/pubmed/34756074
http://dx.doi.org/10.1128/Spectrum.01459-21

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