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A Paal–Knorr agent for chemoproteomic profiling of targets of isoketals in cells

Natural systems produce various γ-dicarbonyl-bearing compounds that can covalently modify lysine in protein targets via the classic Paal–Knorr reaction. Among them is a unique class of lipid-derived electrophiles – isoketals that exhibit high chemical reactivity and critical biological functions. Ho...

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Detalles Bibliográficos
Autores principales:	Wang, Min-Ran, He, Jing-Yang, He, Ji-Xiang, Liu, Ke-Ke, Yang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580055/ https://www.ncbi.nlm.nih.gov/pubmed/34881007 http://dx.doi.org/10.1039/d1sc02230j

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