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Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state

The fungal plasma membrane H(+)-ATPase Pma1 is a vital enzyme, generating a proton-motive force that drives the import of essential nutrients. Autoinhibited Pma1 hexamers in the plasma membrane of starving fungi are activated by glucose signaling and subsequent phosphorylation of the autoinhibitory...

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Detalles Bibliográficos
Autores principales: Heit, Sabine, Geurts, Maxwell M. G., Murphy, Bonnie J., Corey, Robin A., Mills, Deryck J., Kühlbrandt, Werner, Bublitz, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580308/
https://www.ncbi.nlm.nih.gov/pubmed/34757782
http://dx.doi.org/10.1126/sciadv.abj5255