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Profound synchrony of age-specific incidence rates and tumor suppression for different cancer types as revealed by the multistage-senescence model of carcinogenesis

The age-specific trend of cancer incidence rates, but not its magnitude, is well described employing the multistage theory of carcinogenesis by Armitage and Doll in combination with the senescence model of Pompei and Wilson. We derived empirical parameters of the multistage-senescence model from U.S...

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Detalles Bibliográficos
Autores principales: Richardson, Richard B., Anghel, Catalina V., Deng, Dennis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580351/
https://www.ncbi.nlm.nih.gov/pubmed/34695806
http://dx.doi.org/10.18632/aging.203651