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Effect of silibinin on the expression of MMP2, MMP3, MMP9 and TIMP2 in kidney and lung after hepatic ischemia/reperfusion injury in an experimental rat model

PURPOSE: The protective effect of silibinin on kidney and lung parenchyma during hepatic ischemia/reperfusion injury (IRI) is explored. METHODS: Sixty-three Wistar rats were separated into three groups: sham; control (45 min IRI); and silibinin (200 μL silibinin administration after 45 min of ischem...

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Detalles Bibliográficos
Autores principales: Kollaras, Vasileios, Valsami, Georgia, Lambropoulou, Maria, Konstandi, Ourania, Kostomistsopoulos, Nikolaos, Pikoulis, Emmanouil, Simopoulos, Constantinos, Tsaroucha, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580512/
https://www.ncbi.nlm.nih.gov/pubmed/34755764
http://dx.doi.org/10.1590/ACB360904

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