Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection

To advance a novel concept of debulking virus in the oral cavity, the primary site of viral replication, virus-trapping proteins CTB-ACE2 were expressed in chloroplasts and clinical-grade plant material was developed to meet FDA requirements. Chewing gum (2 g) containing plant cells expressed CTB-AC...

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Detalles Bibliográficos
Autores principales: Daniell, Henry, Nair, Smruti K., Esmaeili, Nardana, Wakade, Geetanjali, Shahid, Naila, Ganesan, Prem Kumar, Islam, Md Reyazul, Shepley-McTaggart, Ariel, Feng, Sheng, Gary, Ebony N., Ali, Ali R., Nuth, Manunya, Cruz, Selene Nunez, Graham-Wooten, Jevon, Streatfield, Stephen J., Montoya-Lopez, Ruben, Kaznica, Paul, Mawson, Margaret, Green, Brian J., Ricciardi, Robert, Milone, Michael, Harty, Ronald N., Wang, Ping, Weiner, David B., Margulies, Kenneth B., Collman, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580552/
https://www.ncbi.nlm.nih.gov/pubmed/34774754
http://dx.doi.org/10.1016/j.ymthe.2021.11.008

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