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Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma

Severe trauma can cause systemic reactions, leading to massive bleeding, shock, asphyxia, and disturbance of consciousness. At the same time, patients with severe trauma are at high risk of sepsis and acute renal injury. The occurrence of complications will increase the difficulty of clinical treatm...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Chen, Dan, Wang, Lihua, Li, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580668/
https://www.ncbi.nlm.nih.gov/pubmed/34777535
http://dx.doi.org/10.1155/2021/5754114
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author Zhang, Hong
Chen, Dan
Wang, Lihua
Li, Bing
author_facet Zhang, Hong
Chen, Dan
Wang, Lihua
Li, Bing
author_sort Zhang, Hong
collection PubMed
description Severe trauma can cause systemic reactions, leading to massive bleeding, shock, asphyxia, and disturbance of consciousness. At the same time, patients with severe trauma are at high risk of sepsis and acute renal injury. The occurrence of complications will increase the difficulty of clinical treatment, improve the mortality rate, and bring heavy physical and mental burdens and economic pressure to patients and their families. It is of great clinical significance to understand the high risk factors of sepsis and AKI and actively formulate prevention and treatment measures. In this study, the clinical data of 85 patients with severe trauma were analyzed by univariate and multivariate logistic regression to identify the risk factors leading to sepsis or AKI and analyze the prevention and treatment strategies. The results showed that multiple injuries, APACHE II score on admission, SOFA score on admission, and mechanical ventilation were independent influencing factors of sepsis in patients with severe trauma, while hemorrhagic shock, APACHE II score on admission, CRRT, and sepsis were independent influencing factors of AKI in patients with severe trauma. Severe trauma patients complicated with sepsis or AKI will increase the risk of death. In the course of treatment, prevention and intervention should be given as far as possible to reduce the incidence of complications.
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spelling pubmed-85806682021-11-11 Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma Zhang, Hong Chen, Dan Wang, Lihua Li, Bing Evid Based Complement Alternat Med Research Article Severe trauma can cause systemic reactions, leading to massive bleeding, shock, asphyxia, and disturbance of consciousness. At the same time, patients with severe trauma are at high risk of sepsis and acute renal injury. The occurrence of complications will increase the difficulty of clinical treatment, improve the mortality rate, and bring heavy physical and mental burdens and economic pressure to patients and their families. It is of great clinical significance to understand the high risk factors of sepsis and AKI and actively formulate prevention and treatment measures. In this study, the clinical data of 85 patients with severe trauma were analyzed by univariate and multivariate logistic regression to identify the risk factors leading to sepsis or AKI and analyze the prevention and treatment strategies. The results showed that multiple injuries, APACHE II score on admission, SOFA score on admission, and mechanical ventilation were independent influencing factors of sepsis in patients with severe trauma, while hemorrhagic shock, APACHE II score on admission, CRRT, and sepsis were independent influencing factors of AKI in patients with severe trauma. Severe trauma patients complicated with sepsis or AKI will increase the risk of death. In the course of treatment, prevention and intervention should be given as far as possible to reduce the incidence of complications. Hindawi 2021-11-03 /pmc/articles/PMC8580668/ /pubmed/34777535 http://dx.doi.org/10.1155/2021/5754114 Text en Copyright © 2021 Hong Zhang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Hong
Chen, Dan
Wang, Lihua
Li, Bing
Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_full Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_fullStr Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_full_unstemmed Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_short Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_sort influencing factors and prevention of sepsis or acute kidney injury in 85 patients with severe trauma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580668/
https://www.ncbi.nlm.nih.gov/pubmed/34777535
http://dx.doi.org/10.1155/2021/5754114
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