Cargando…

Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel

Chemotherapy for multiple primary malignancies is challenging. We herein report a case of synchronous primary lung adenocarcinoma and hepatocellular carcinoma (HCC). A 72-year-old man was admitted for the evaluation of an abnormal shadow on his lung. Computed tomography revealed a lung nodule in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Egawa, Takashi, Masuzawa, Keita, Nakayama, Sohei, Maeda, Ichiro, Tsunematsu, Satoshi, Suzuki, Yukio, Suzuki, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580750/
https://www.ncbi.nlm.nih.gov/pubmed/33840693
http://dx.doi.org/10.2169/internalmedicine.6442-20
_version_ 1784596667068055552
author Egawa, Takashi
Masuzawa, Keita
Nakayama, Sohei
Maeda, Ichiro
Tsunematsu, Satoshi
Suzuki, Yukio
Suzuki, Yusuke
author_facet Egawa, Takashi
Masuzawa, Keita
Nakayama, Sohei
Maeda, Ichiro
Tsunematsu, Satoshi
Suzuki, Yukio
Suzuki, Yusuke
author_sort Egawa, Takashi
collection PubMed
description Chemotherapy for multiple primary malignancies is challenging. We herein report a case of synchronous primary lung adenocarcinoma and hepatocellular carcinoma (HCC). A 72-year-old man was admitted for the evaluation of an abnormal shadow on his lung. Computed tomography revealed a lung nodule in the right upper lobe and multiple liver masses. He was diagnosed with synchronous primary lung adenocarcinoma and HCC. Atezolizumab, bevacizumab, carboplatin, and paclitaxel (ABCP) chemotherapy was efficacious for both tumors. ABCP chemotherapy may be a potential treatment option for synchronous primary lung adenocarcinoma and HCC.
format Online
Article
Text
id pubmed-8580750
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-85807502021-11-19 Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel Egawa, Takashi Masuzawa, Keita Nakayama, Sohei Maeda, Ichiro Tsunematsu, Satoshi Suzuki, Yukio Suzuki, Yusuke Intern Med Case Report Chemotherapy for multiple primary malignancies is challenging. We herein report a case of synchronous primary lung adenocarcinoma and hepatocellular carcinoma (HCC). A 72-year-old man was admitted for the evaluation of an abnormal shadow on his lung. Computed tomography revealed a lung nodule in the right upper lobe and multiple liver masses. He was diagnosed with synchronous primary lung adenocarcinoma and HCC. Atezolizumab, bevacizumab, carboplatin, and paclitaxel (ABCP) chemotherapy was efficacious for both tumors. ABCP chemotherapy may be a potential treatment option for synchronous primary lung adenocarcinoma and HCC. The Japanese Society of Internal Medicine 2021-04-12 2021-10-15 /pmc/articles/PMC8580750/ /pubmed/33840693 http://dx.doi.org/10.2169/internalmedicine.6442-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Egawa, Takashi
Masuzawa, Keita
Nakayama, Sohei
Maeda, Ichiro
Tsunematsu, Satoshi
Suzuki, Yukio
Suzuki, Yusuke
Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel
title Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel
title_full Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel
title_fullStr Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel
title_full_unstemmed Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel
title_short Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel
title_sort synchronous primary lung adenocarcinoma and hepatocellular carcinoma successfully treated with a combination of atezolizumab, bevacizumab, carboplatin, and paclitaxel
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580750/
https://www.ncbi.nlm.nih.gov/pubmed/33840693
http://dx.doi.org/10.2169/internalmedicine.6442-20
work_keys_str_mv AT egawatakashi synchronousprimarylungadenocarcinomaandhepatocellularcarcinomasuccessfullytreatedwithacombinationofatezolizumabbevacizumabcarboplatinandpaclitaxel
AT masuzawakeita synchronousprimarylungadenocarcinomaandhepatocellularcarcinomasuccessfullytreatedwithacombinationofatezolizumabbevacizumabcarboplatinandpaclitaxel
AT nakayamasohei synchronousprimarylungadenocarcinomaandhepatocellularcarcinomasuccessfullytreatedwithacombinationofatezolizumabbevacizumabcarboplatinandpaclitaxel
AT maedaichiro synchronousprimarylungadenocarcinomaandhepatocellularcarcinomasuccessfullytreatedwithacombinationofatezolizumabbevacizumabcarboplatinandpaclitaxel
AT tsunematsusatoshi synchronousprimarylungadenocarcinomaandhepatocellularcarcinomasuccessfullytreatedwithacombinationofatezolizumabbevacizumabcarboplatinandpaclitaxel
AT suzukiyukio synchronousprimarylungadenocarcinomaandhepatocellularcarcinomasuccessfullytreatedwithacombinationofatezolizumabbevacizumabcarboplatinandpaclitaxel
AT suzukiyusuke synchronousprimarylungadenocarcinomaandhepatocellularcarcinomasuccessfullytreatedwithacombinationofatezolizumabbevacizumabcarboplatinandpaclitaxel