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Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel (LCIG) is an established device-aided therapy for advanced Parkinson's disease (PD). Phytobezoar associated with LCIG is a rare device-related complication and presents with exacerbations of gastrointestinal and PD symptoms....

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Autores principales: Ueno, Tatsuya, Hanabata, Norihiro, Katagai, Atsuko, Okudera, Rena, Arai, Akira, Tomiyama, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580754/
https://www.ncbi.nlm.nih.gov/pubmed/33867393
http://dx.doi.org/10.2169/internalmedicine.7210-21
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author Ueno, Tatsuya
Hanabata, Norihiro
Katagai, Atsuko
Okudera, Rena
Arai, Akira
Tomiyama, Masahiko
author_facet Ueno, Tatsuya
Hanabata, Norihiro
Katagai, Atsuko
Okudera, Rena
Arai, Akira
Tomiyama, Masahiko
author_sort Ueno, Tatsuya
collection PubMed
description Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel (LCIG) is an established device-aided therapy for advanced Parkinson's disease (PD). Phytobezoar associated with LCIG is a rare device-related complication and presents with exacerbations of gastrointestinal and PD symptoms. We herein report the case of a phytobezoar that was formed at a knot on the pigtail-shaped J-tube and developed only in association with postprandial abdominal pain, similar to a feeling of a tube being pulled in without an exacerbation of PD symptoms. Such abdominal pain may be a warning sign of phytobezoar in LCIG-treated patients. Despite device-related complications, high-pressure alarms are not always present, and PD symptoms are not always exacerbated.
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spelling pubmed-85807542021-11-19 Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review Ueno, Tatsuya Hanabata, Norihiro Katagai, Atsuko Okudera, Rena Arai, Akira Tomiyama, Masahiko Intern Med Case Report Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel (LCIG) is an established device-aided therapy for advanced Parkinson's disease (PD). Phytobezoar associated with LCIG is a rare device-related complication and presents with exacerbations of gastrointestinal and PD symptoms. We herein report the case of a phytobezoar that was formed at a knot on the pigtail-shaped J-tube and developed only in association with postprandial abdominal pain, similar to a feeling of a tube being pulled in without an exacerbation of PD symptoms. Such abdominal pain may be a warning sign of phytobezoar in LCIG-treated patients. Despite device-related complications, high-pressure alarms are not always present, and PD symptoms are not always exacerbated. The Japanese Society of Internal Medicine 2021-04-19 2021-10-15 /pmc/articles/PMC8580754/ /pubmed/33867393 http://dx.doi.org/10.2169/internalmedicine.7210-21 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ueno, Tatsuya
Hanabata, Norihiro
Katagai, Atsuko
Okudera, Rena
Arai, Akira
Tomiyama, Masahiko
Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review
title Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review
title_full Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review
title_fullStr Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review
title_full_unstemmed Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review
title_short Phytobezoar Associated with Levodopa-carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease: A Case Report and Literature Review
title_sort phytobezoar associated with levodopa-carbidopa intestinal gel infusion in patients with parkinson's disease: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580754/
https://www.ncbi.nlm.nih.gov/pubmed/33867393
http://dx.doi.org/10.2169/internalmedicine.7210-21
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