A molecular toolbox for ADP-ribosyl binding proteins

Proteins interacting with ADP-ribosyl groups are often involved in disease-related pathways or viral infections, making them attractive drug targets. We present a robust and accessible assay applicable to both hydrolyzing or non-hydrolyzing binders of mono- and poly-ADP-ribosyl groups. This technolo...

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Detalles Bibliográficos
Autores principales: Sowa, Sven T., Galera-Prat, Albert, Wazir, Sarah, Alanen, Heli I., Maksimainen, Mirko M., Lehtiö, Lari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580838/
https://www.ncbi.nlm.nih.gov/pubmed/34786571
http://dx.doi.org/10.1016/j.crmeth.2021.100121

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