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Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic()

We present a formal mathematical modeling framework for a multi-agent sequential decision problem during an epidemic. The problem is formulated as a collaboration between a vaccination agent and learning agent to allocate stockpiles of vaccines and tests to a set of zones under various types of unce...

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Detalles Bibliográficos
Autores principales: Thul, Lawrence, Powell, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580866/
https://www.ncbi.nlm.nih.gov/pubmed/34785854
http://dx.doi.org/10.1016/j.ejor.2021.11.007
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author Thul, Lawrence
Powell, Warren
author_facet Thul, Lawrence
Powell, Warren
author_sort Thul, Lawrence
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description We present a formal mathematical modeling framework for a multi-agent sequential decision problem during an epidemic. The problem is formulated as a collaboration between a vaccination agent and learning agent to allocate stockpiles of vaccines and tests to a set of zones under various types of uncertainty. The model is able to capture passive information processes and maintain beliefs over the uncertain state of the world. We designed a parameterized direct lookahead approximation which is robust and scalable under different scenarios, resource scarcity, and beliefs about the environment. We design a test allocation policy designed to capture the value of information and demonstrate that it outperforms other learning policies when there is an extreme shortage of resources (information is scarce). We simulate the model with two scenarios including a resource allocation problem to each state in the United States and another for the nursing homes in Nevada. The US example demonstrates the scalability of the model and the nursing home example demonstrates the robustness under extreme resource shortages.
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spelling pubmed-85808662021-11-12 Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic() Thul, Lawrence Powell, Warren Eur J Oper Res Article We present a formal mathematical modeling framework for a multi-agent sequential decision problem during an epidemic. The problem is formulated as a collaboration between a vaccination agent and learning agent to allocate stockpiles of vaccines and tests to a set of zones under various types of uncertainty. The model is able to capture passive information processes and maintain beliefs over the uncertain state of the world. We designed a parameterized direct lookahead approximation which is robust and scalable under different scenarios, resource scarcity, and beliefs about the environment. We design a test allocation policy designed to capture the value of information and demonstrate that it outperforms other learning policies when there is an extreme shortage of resources (information is scarce). We simulate the model with two scenarios including a resource allocation problem to each state in the United States and another for the nursing homes in Nevada. The US example demonstrates the scalability of the model and the nursing home example demonstrates the robustness under extreme resource shortages. Elsevier B.V. 2023-01-01 2021-11-11 /pmc/articles/PMC8580866/ /pubmed/34785854 http://dx.doi.org/10.1016/j.ejor.2021.11.007 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Thul, Lawrence
Powell, Warren
Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic()
title Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic()
title_full Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic()
title_fullStr Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic()
title_full_unstemmed Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic()
title_short Stochastic optimization for vaccine and testing kit allocation for the COVID-19 pandemic()
title_sort stochastic optimization for vaccine and testing kit allocation for the covid-19 pandemic()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580866/
https://www.ncbi.nlm.nih.gov/pubmed/34785854
http://dx.doi.org/10.1016/j.ejor.2021.11.007
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