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proBDNF expression induces apoptosis and inhibits synaptic regeneration by regulating the RhoA-JNK pathway in an in vitro post-stroke depression model

Brain-derived neurotrophic factor (BDNF) plays an important role in the pathophysiology of post-stroke depression (PSD). However, the precise function and potential mechanism of proBDNF, the precursor form of BDNF, are unknown. In our study, a PSD-like model was established by treating neuronal cell...

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Detalles Bibliográficos
Autores principales:	Yang, Bangkun, Wang, Lesheng, Nie, Ying, Wei, Wei, Xiong, Wenping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580986/ https://www.ncbi.nlm.nih.gov/pubmed/34759285 http://dx.doi.org/10.1038/s41398-021-01667-2

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