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Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function

Preclinical rodent models suggest that psychosis involves alterations in the activity and glutamatergic function in the hippocampus, driving dopamine activity through projections to the striatum. The extent to which this model applies to the onset of psychosis in clinical subjects is unclear. We ass...

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Detalles Bibliográficos
Autores principales:	Allen, Paul, Hird, Emily J., Orlov, Natasza, Modinos, Gemma, Bossong, Matthijs, Antoniades, Mathilde, Sampson, Carly, Azis, Matilda, Howes, Oliver, Stone, James, Perez, Jesus, Broome, Matthew, Grace, Anthony A., McGuire, Philip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580992/ https://www.ncbi.nlm.nih.gov/pubmed/34759289 http://dx.doi.org/10.1038/s41398-021-01705-z

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