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β-Adrenergic signaling induces Notch-mediated salivary gland progenitor cell control
β-Adrenergic signaling blockade is a mainstay of hypertension management. One percent of patients taking β-blockers develop reduced salivary gland (SG) function. Here we investigate the role of SG progenitor cells in β-blocker-induced hyposalivation, using human SG organoid cultures (SGOs). Compared...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581054/ https://www.ncbi.nlm.nih.gov/pubmed/34678204 http://dx.doi.org/10.1016/j.stemcr.2021.09.015 |