Multifunctional, TNF-α and IFN-γ-Secreting CD4 and CD8 T Cells and CD8(High) T Cells Are Associated With the Cure of Human Visceral Leishmaniasis

Visceral leishmaniasis (VL) is a chronic and often fatal disease caused by protozoans of the genus Leishmania that affects millions of people worldwide. Patients with symptomatic VL have an impaired anti-Leishmania-specific CD4(+) T-cell response, which is reversed after clinical cure. In contrast,...

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Detalles Bibliográficos
Autores principales: Rodrigues, Lorranny Santana, Barreto, Aline Silva, Bomfim, Lays Gisele Santos, Gomes, Marcos Couto, Ferreira, Nathalia Luisa Carlos, da Cruz, Geydson Silveira, Magalhães, Lucas Sousa, de Jesus, Amélia Ribeiro, Palatnik-de-Sousa, Clarisa B., Corrêa, Cristiane Bani, de Almeida, Roque Pacheco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581227/
https://www.ncbi.nlm.nih.gov/pubmed/34777391
http://dx.doi.org/10.3389/fimmu.2021.773983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581227/
https://www.ncbi.nlm.nih.gov/pubmed/34777391
http://dx.doi.org/10.3389/fimmu.2021.773983

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