Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System

Traditional Chinese medicine (TCM) has demonstrated superior therapeutic effect for musculoskeletal diseases for thousands of years. Recently, the herbal extracts of TCM have received rapid advances in musculoskeletal tissue engineering (MTE). A literature review collecting both English and Chinese...

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Autores principales: Li, Haotao, Wu, Rongjie, Yu, Haiyang, Zheng, Qiujian, Chen, Yuanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581265/
https://www.ncbi.nlm.nih.gov/pubmed/34776987
http://dx.doi.org/10.3389/fphar.2021.778041
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author Li, Haotao
Wu, Rongjie
Yu, Haiyang
Zheng, Qiujian
Chen, Yuanfeng
author_facet Li, Haotao
Wu, Rongjie
Yu, Haiyang
Zheng, Qiujian
Chen, Yuanfeng
author_sort Li, Haotao
collection PubMed
description Traditional Chinese medicine (TCM) has demonstrated superior therapeutic effect for musculoskeletal diseases for thousands of years. Recently, the herbal extracts of TCM have received rapid advances in musculoskeletal tissue engineering (MTE). A literature review collecting both English and Chinese references on bioactive herbal extracts of TCM in biomaterial-based approaches was performed. This review provides an up-to-date overview of application of TCMs in the field of MTE, involving regulation of multiple signaling pathways in osteogenesis, angiogenesis, anti-inflammation, and chondrogenesis. Meanwhile, we highlight the potential advantages of TCM, opening the possibility of its extensive application in MTE. Overall, the superiority of traditional Chinese medicine turns it into an attractive candidate for coupling with advanced additive manufacturing technology.
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spelling pubmed-85812652021-11-12 Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System Li, Haotao Wu, Rongjie Yu, Haiyang Zheng, Qiujian Chen, Yuanfeng Front Pharmacol Pharmacology Traditional Chinese medicine (TCM) has demonstrated superior therapeutic effect for musculoskeletal diseases for thousands of years. Recently, the herbal extracts of TCM have received rapid advances in musculoskeletal tissue engineering (MTE). A literature review collecting both English and Chinese references on bioactive herbal extracts of TCM in biomaterial-based approaches was performed. This review provides an up-to-date overview of application of TCMs in the field of MTE, involving regulation of multiple signaling pathways in osteogenesis, angiogenesis, anti-inflammation, and chondrogenesis. Meanwhile, we highlight the potential advantages of TCM, opening the possibility of its extensive application in MTE. Overall, the superiority of traditional Chinese medicine turns it into an attractive candidate for coupling with advanced additive manufacturing technology. Frontiers Media S.A. 2021-10-28 /pmc/articles/PMC8581265/ /pubmed/34776987 http://dx.doi.org/10.3389/fphar.2021.778041 Text en Copyright © 2021 Li, Wu, Yu, Zheng and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Li, Haotao
Wu, Rongjie
Yu, Haiyang
Zheng, Qiujian
Chen, Yuanfeng
Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System
title Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System
title_full Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System
title_fullStr Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System
title_full_unstemmed Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System
title_short Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System
title_sort bioactive herbal extracts of traditional chinese medicine applied with the biomaterials: for the current applications and advances in the musculoskeletal system
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581265/
https://www.ncbi.nlm.nih.gov/pubmed/34776987
http://dx.doi.org/10.3389/fphar.2021.778041
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