Cargando…

GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway

Emerging evidence indicates extensive oxidative stress is a consequence of obesity which impairs bone formation. Glutathione peroxidase 7 (GPX7) is a conserved endoplasmic reticulum (ER) retention protein, lacking of which causes accumulation of reactive oxygen species (ROS) and promotes adipogenesi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Xuchen, Li, Boer, Wu, Fanzi, Liu, Xiaoyu, Liu, Mengyu, Wang, Chenglin, Shi, Yu, Ye, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581313/
https://www.ncbi.nlm.nih.gov/pubmed/34626080
http://dx.doi.org/10.1111/jcmm.16974