Cargando…

GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway

Emerging evidence indicates extensive oxidative stress is a consequence of obesity which impairs bone formation. Glutathione peroxidase 7 (GPX7) is a conserved endoplasmic reticulum (ER) retention protein, lacking of which causes accumulation of reactive oxygen species (ROS) and promotes adipogenesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Xuchen, Li, Boer, Wu, Fanzi, Liu, Xiaoyu, Liu, Mengyu, Wang, Chenglin, Shi, Yu, Ye, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581313/ https://www.ncbi.nlm.nih.gov/pubmed/34626080 http://dx.doi.org/10.1111/jcmm.16974

Ejemplares similares

Translational Regulation of GPx-1 and GPx-4 by the mTOR Pathway
por: Reinke, Emily N., et al.
Publicado: (2014)

Attenuates of NAD(+) impair BMSC osteogenesis and fracture repair through OXPHOS
por: Li, Boer, et al.
Publicado: (2022)

Wnt7b Inhibits Osteoclastogenesis via AKT Activation and Glucose Metabolic Rewiring
por: Wu, Fanzi, et al.
Publicado: (2021)

FGF7-induced E11 facilitates cell-cell communication through connexin43
por: Liu, Xiaoyu, et al.
Publicado: (2021)

Tocopherol attenuates the oxidative stress of BMSCs by inhibiting ferroptosis through the PI3k/AKT/mTOR pathway
por: Lan, Dongmei, et al.
Publicado: (2022)

Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs)
por: Yan, Yan, et al.
Publicado: (2020)

Endogenous Aβ induces osteoporosis through an mTOR-dependent inhibition of autophagy in bone marrow mesenchymal stem cells (BMSCs)
por: Lin, Ye, et al.
Publicado: (2021)

Leonurine Promotes the Osteoblast Differentiation of Rat BMSCs by Activation of Autophagy via the PI3K/Akt/mTOR Pathway
por: Zhao, Bingkun, et al.
Publicado: (2021)

Erratum: Tocopherol attenuates the oxidative stress of BMSCs by inhibiting ferroptosis through the PI3k/AKT/mTOR pathway
por: Frontiers Production Office,
Publicado: (2023)

Alpinetin alleviates osteoporosis by promoting osteogenic differentiation in BMSCs by triggering autophagy via PKA/mTOR/ULK1 signaling
por: Zeng, Chenying, et al.
Publicado: (2022)

Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer
por: Mazumdar, Abhijit, et al.
Publicado: (2022)

Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway
por: Liang, Hao-Yu, et al.
Publicado: (2022)

GPX4 and GPX7 Over-Expression in Human Hepatocellular Carcinoma Tissues
por: Guerriero, E., et al.
Publicado: (2015)

GPX2 promotes EMT and metastasis in non‐small cell lung cancer by activating PI3K/AKT/mTOR/Snail signaling axis
por: Peng, Fang, et al.
Publicado: (2023)

Toxic Effects of Indoxyl Sulfate on Osteoclastogenesis and Osteoblastogenesis
por: Shyu, Jia-Fwu, et al.
Publicado: (2021)

Hedgehog Activation Regulates Human Osteoblastogenesis
por: Onodera, Shoko, et al.
Publicado: (2020)

FZD7 regulates BMSCs-mediated protection of CML cells
por: Liu, Na, et al.
Publicado: (2015)

Rubidium Chloride Targets Jnk/p38-Mediated NF-κB Activation to Attenuate Osteoclastogenesis and Facilitate Osteoblastogenesis
por: Ouyang, Zhengxiao, et al.
Publicado: (2019)

Extracellular Vesicles from BMSCs Prevent Glucocorticoid-Induced BMECs Injury by Regulating Autophagy via the PI3K/Akt/mTOR Pathway
por: Ma, Jinhui, et al.
Publicado: (2022)

Timosaponin AIII Is Preferentially Cytotoxic to Tumor Cells through Inhibition of mTOR and Induction of ER Stress
por: King, Frank W., et al.
Publicado: (2009)

Glucose Regulation of Load‐Induced mTOR Signaling and ER Stress in Mammalian Heart
por: Sen, Shiraj, et al.
Publicado: (2013)

Drugging the PI3K/AKT/mTOR Pathway in ER+ Breast Cancer
por: Alves, Carla L., et al.
Publicado: (2023)

GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma
por: Zhou, Yan, et al.
Publicado: (2022)

Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells
por: Sun, Yadong, et al.
Publicado: (2021)

Effect of Salicornia herbacea on Osteoblastogenesis and Adipogenesis in Vitro
por: Karadeniz, Fatih, et al.
Publicado: (2014)

Lansoprazole Upregulates Polyubiquitination of the TNF Receptor-Associated Factor 6 and Facilitates Runx2-mediated Osteoblastogenesis
por: Mishima, Kenichi, et al.
Publicado: (2015)

Restoration of Regenerative Osteoblastogenesis in Aged Mice: Modulation of TNF
por: Wahl, Elizabeth C, et al.
Publicado: (2010)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Heterodimeric BMP-2/7 Antagonizes the Inhibition of All-Trans Retinoic Acid and Promotes the Osteoblastogenesis
por: Bi, Wenjuan, et al.
Publicado: (2013)

The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification
por: Jiang, Wenhong, et al.
Publicado: (2021)

Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis
por: Boyce, Brendan F., et al.
Publicado: (2023)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

Dynamic mechanical loading facilitated chondrogenic differentiation of rabbit BMSCs in collagen scaffolds
por: Cao, Wanxu, et al.
Publicado: (2019)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal
por: Fan, Bin, et al.
Publicado: (2017)

Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway
por: Wu, Tao, et al.
Publicado: (2015)

Control of mTOR Signaling by Ubiquitin
por: Jiang, Yao, et al.
Publicado: (2019)

Petroleum Ether Extract of Cissus Quadrangularis (Linn.) Enhances Bone Marrow Mesenchymal Stem Cell Proliferation and Facilitates Osteoblastogenesis
por: Potu, Bhagath Kumar, et al.
Publicado: (2009)

KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy
por: Wang, Yi, et al.
Publicado: (2021)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_00fum6d3c74aiq5chh8r3r8se4