Therapeutic potential of parkin as a tumor suppressor via transcriptional control of cyclins in glioblastoma cell and animal models

Parkin (PK) is an E3-ligase harboring tumor suppressor properties that has been associated to various cancer types including glioblastoma (GBM). However, PK is also a transcription factor (TF), the contribution of which to GBM etiology remains to be established. Methods: The impact of PK on GBM cell...

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Detalles Bibliográficos
Autores principales: Rouland, Lila, Duplan, Eric, Ramos dos Santos, Lígia, Bernardin, Aurore, Katula, Karen S., Manfioletti, Guidalberto, Idbaih, Ahmed, Checler, Frédéric, Alves da Costa, Cristine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581414/
https://www.ncbi.nlm.nih.gov/pubmed/34815803
http://dx.doi.org/10.7150/thno.57549

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