CRTC3, a sensor and key regulator for melanogenesis, as a tunable therapeutic target for pigmentary disorders

Background: Although CREB phosphorylation is known to be essential in UVB/cAMP-stimulated melanogenesis, CREB null mice did not show identifiable pigmentation phenotypes. Here, we show that CREB-regulated transcription co-activator 3 (CRTC3) quantitatively regulates and orchestrates melanogenesis by...

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Detalles Bibliográficos
Autores principales: Yoo, Hanju, Lee, Ha-Ri, Kim, Ki-Hyun, Kim, Min-Ah, Bang, Seunghyun, Kang, Young-Ho, Kim, Woo-hyung, Song, Youngsup, Chang, Sung Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581419/
https://www.ncbi.nlm.nih.gov/pubmed/34815795
http://dx.doi.org/10.7150/thno.66378

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