Extracellular vesicles fail to trigger the generation of new cardiomyocytes in chronically infarcted hearts

Background: Extracellular vesicles (EV) mediate the therapeutic effects of stem cells but it is unclear whether this involves cardiac regeneration mediated by endogenous cardiomyocyte proliferation. Methods: Bi-transgenic MerCreMer/ZEG (n = 15/group) and Mosaic Analysis With Double Markers (MADM; n...

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Detalles Bibliográficos
Autores principales: Lima Correa, Bruna, El Harane, Nadia, Desgres, Manon, Perotto, Maria, Alayrac, Paul, Guillas, Chloé, Pidial, Laetitia, Bellamy, Valérie, Baron, Emilie, Autret, Gwennhael, Kamaleswaran, Keirththana, Pezzana, Chloé, Perier, Marie-Cécile, Vilar, José, Alberdi, Antonio, Brisson, Alain, Renault, Nisa, Gnecchi, Massimiliano, Silvestre, Jean-Sébastien, Menasché, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581432/
https://www.ncbi.nlm.nih.gov/pubmed/34815807
http://dx.doi.org/10.7150/thno.62304

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