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The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau
Tau35 is a truncated form of tau found in human brain in a subset of tauopathies. Tau35 expression in mice recapitulates key features of human disease, including progressive increase in tau phosphorylation, along with cognitive and motor dysfunction. The appearance of aggregated tau suggests that Ta...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581542/ https://www.ncbi.nlm.nih.gov/pubmed/34778381 http://dx.doi.org/10.3389/fmolb.2021.779240 |