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Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
Light sensitivity of the vertebrate retina relies on the integrity of photoreceptors, including rods and cones. Research in patients with Alzheimer's disease (AD) and in AD transgenic mice reports that accumulated amyloid-β (Aβ) plaques in the retina are toxic to retinal neurons. Moreover, Aβ p...
Autores principales: | Zhang, Jie, Gao, Feng, Ma, Yuqian, Xue, Tian, Shen, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581578/ https://www.ncbi.nlm.nih.gov/pubmed/34805789 http://dx.doi.org/10.1016/j.isci.2021.103327 |
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