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Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease

Light sensitivity of the vertebrate retina relies on the integrity of photoreceptors, including rods and cones. Research in patients with Alzheimer's disease (AD) and in AD transgenic mice reports that accumulated amyloid-β (Aβ) plaques in the retina are toxic to retinal neurons. Moreover, Aβ p...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Gao, Feng, Ma, Yuqian, Xue, Tian, Shen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581578/
https://www.ncbi.nlm.nih.gov/pubmed/34805789
http://dx.doi.org/10.1016/j.isci.2021.103327

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