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Unraveling the Effects of a Talimogene Laherparepvec (T-VEC)-Induced Tumor Oncolysate on Myeloid Dendritic Cells

T-VEC, a HSV-1 derived oncolytic virus, is approved for the treatment of advanced melanoma. The mechanisms that underly the systemic anti-tumor effect that is seen following intratumoral injection have not yet been studied but are likely to be mediated by myeloid dendritic cells (myDC) that initiate...

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Detalles Bibliográficos
Autores principales:	Tijtgat, Jens, De Munck, Jolien, Dufait, Inès, Schwarze, Julia Katharina, Van Riet, Ivan, Franceschini, Lorenzo, Breckpot, Karine, Aerts, Joeri L., Neyns, Bart, Tuyaerts, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581672/ https://www.ncbi.nlm.nih.gov/pubmed/34777344 http://dx.doi.org/10.3389/fimmu.2021.733506

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