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Controlling the SARS-CoV-2 spike glycoprotein conformation

The coronavirus (CoV) spike (S) protein, involved in viral–host cell fusion, is the primary immunogenic target for virus neutralization and the current focus of many vaccine design efforts. The highly flexible S-protein, with its mobile domains, presents a moving target to the immune system. Here, t...

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Detalles Bibliográficos
Autores principales: Henderson, Rory, Edwards, Robert J., Mansouri, Katayoun, Janowska, Katarzyna, Stalls, Victoria, Gobeil, Sophie, Kopp, Megan, Li, Dapeng, Parks, Rob, Hsu, Allen L., Borgnia, Mario J., Haynes, Barton F., Acharya, Priyamvada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581954/
https://www.ncbi.nlm.nih.gov/pubmed/32699321
http://dx.doi.org/10.1038/s41594-020-0479-4