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Nanolipoprotein-Mediated Her2 Protein Transfection Induces Malignant Transformation in Human Breast Acinar Cultures

[Image: see text] Her2 overexpression is associated with an aggressive form of breast cancer and malignant transformation. We demonstrate in this work that nanolipoprotein particles (NLPs) synthesized in a cell-free manner can be used to transfer Her2 protein into the membrane of nonmalignant cells...

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Detalles Bibliográficos
Autores principales: He, Wei, Evans, Angela C., Hynes, William F., Coleman, Matthew A., Robertson, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581977/
https://www.ncbi.nlm.nih.gov/pubmed/34778614
http://dx.doi.org/10.1021/acsomega.1c03086