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Interaction and Inhibition of a Ganoderma lucidum Proteoglycan on PTP1B Activity for Anti-diabetes

[Image: see text] Protein tyrosine phosphatase 1B (PTP1B) is a key negative regulator of insulin and an effective target for the treatment of type 2 diabetes (T2D). A natural hyperbranched proteoglycan extracted from Ganoderma lucidum, namely, Fudan-Yueyang G. Lucidum (FYGL), was demonstrated capabl...

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Detalles Bibliográficos
Autores principales:	Yu, Fanzhen, Wang, Yingxin, Teng, Yilong, Yang, Shutong, He, Yanming, Zhang, Zeng, Yang, Hongjie, Ding, Chuan-Fan, Zhou, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582033/ https://www.ncbi.nlm.nih.gov/pubmed/34778653 http://dx.doi.org/10.1021/acsomega.1c04244

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