Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility

Aged males disproportionately succumb to increased COVID-19 severity, hospitalization, and mortality compared to females. Angiotensin-converting enzyme 2 (ACE2) and transmembrane protease, serine 2 (TMPRSS2) facilitate SARS-CoV-2 viral entry and may have sexually dimorphic regulation. As viral load...

Descripción completa

Detalles Bibliográficos
Autores principales: Viveiros, Anissa, Gheblawi, Mahmoud, Aujla, Preetinder K., Sosnowski, Deanna K., Seubert, John M., Kassiri, Zamaneh, Oudit, Gavin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582230/
https://www.ncbi.nlm.nih.gov/pubmed/34774871
http://dx.doi.org/10.1016/j.yjmcc.2021.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582230/
https://www.ncbi.nlm.nih.gov/pubmed/34774871
http://dx.doi.org/10.1016/j.yjmcc.2021.11.003

Ejemplares similares