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Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility

Aged males disproportionately succumb to increased COVID-19 severity, hospitalization, and mortality compared to females. Angiotensin-converting enzyme 2 (ACE2) and transmembrane protease, serine 2 (TMPRSS2) facilitate SARS-CoV-2 viral entry and may have sexually dimorphic regulation. As viral load...

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Detalles Bibliográficos
Autores principales:	Viveiros, Anissa, Gheblawi, Mahmoud, Aujla, Preetinder K., Sosnowski, Deanna K., Seubert, John M., Kassiri, Zamaneh, Oudit, Gavin Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582230/ https://www.ncbi.nlm.nih.gov/pubmed/34774871 http://dx.doi.org/10.1016/j.yjmcc.2021.11.003

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