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Targeting of HSP70/HSF1 Axis Abrogates In Vitro Ibrutinib-Resistance in Chronic Lymphocytic Leukemia
SIMPLE SUMMARY: The use of ibrutinib has changed the management and clinical history of patients with multiple-treated chronic lymphocytic leukemia (CLL). Nevertheless, an increasing number of patients develop resistance to treatment, with mechanisms still to be fully clarified. Since HSP70 plays a...
Autores principales: | Frezzato, Federica, Visentin, Andrea, Severin, Filippo, Pizzo, Serena, Ruggeri, Edoardo, Mouawad, Nayla, Martinello, Leonardo, Pagnin, Elisa, Trimarco, Valentina, Tonini, Alessia, Carraro, Samuela, Pravato, Stefano, Imbergamo, Silvia, Manni, Sabrina, Piazza, Francesco, Brunati, Anna Maria, Facco, Monica, Trentin, Livio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582437/ https://www.ncbi.nlm.nih.gov/pubmed/34771616 http://dx.doi.org/10.3390/cancers13215453 |
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