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Locus-Specific DNA Methylation Editing in Melanoma Cell Lines Using a CRISPR-Based System

SIMPLE SUMMARY: DNA methylation is an important modification of the genome that is implicated in the pathogenesis of numerous human diseases, including cancer. DNA methylation changes can alter the expression of critical genes, predisposing to disease progression. Existing techniques that can modify...

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Detalles Bibliográficos
Autores principales:	Smith, Jim, Banerjee, Rakesh, Waly, Reema, Urbano, Arthur, Gimenez, Gregory, Day, Robert, Eccles, Michael R., Weeks, Robert J., Chatterjee, Aniruddha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582460/ https://www.ncbi.nlm.nih.gov/pubmed/34771597 http://dx.doi.org/10.3390/cancers13215433

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