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Resistance Mechanisms to Combined CDK4/6 Inhibitors and Endocrine Therapy in ER+/HER2− Advanced Breast Cancer: Biomarkers and Potential Novel Treatment Strategies

SIMPLE SUMMARY: Advanced stage breast cancer is incurable, and a leading cause of cancer-related death in women. Recently, novel treatment options have improved clinical outcomes of breast cancer patients. Combined CDK4/6 inhibitor and endocrine therapy have been shown to be highly effective, improv...

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Detalles Bibliográficos
Autores principales: Al-Qasem, Abeer J., Alves, Carla L., Ditzel, Henrik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582464/
https://www.ncbi.nlm.nih.gov/pubmed/34771560
http://dx.doi.org/10.3390/cancers13215397