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Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study
SIMPLE SUMMARY: Dietary habits are one of the factors that influence the development of gastric cancer and, although it has been seen that the Mediterranean diet has a protective effect on this type of cancer, there are different indexes to assess the degree of adherence to this dietary pattern; thi...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582518/ https://www.ncbi.nlm.nih.gov/pubmed/34771444 http://dx.doi.org/10.3390/cancers13215281 |
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author | Álvarez-Álvarez, Laura Vitelli-Storelli, Facundo Rubín-García, María Aragonés, Nuria Ardanaz, Eva Castaño-Vinyals, Gemma Obón-Santacana, Mireia Dierssen-Sotos, Trinidad Salas-Trejo, Dolores Tardón, Adonina Moleón, José Juan Jiménez Alguacil, Juan Chirlaque, María Dolores Pérez-Gómez, Beatriz Pollán, Marina Kogevinas, Manolis Martín, Vicente |
author_facet | Álvarez-Álvarez, Laura Vitelli-Storelli, Facundo Rubín-García, María Aragonés, Nuria Ardanaz, Eva Castaño-Vinyals, Gemma Obón-Santacana, Mireia Dierssen-Sotos, Trinidad Salas-Trejo, Dolores Tardón, Adonina Moleón, José Juan Jiménez Alguacil, Juan Chirlaque, María Dolores Pérez-Gómez, Beatriz Pollán, Marina Kogevinas, Manolis Martín, Vicente |
author_sort | Álvarez-Álvarez, Laura |
collection | PubMed |
description | SIMPLE SUMMARY: Dietary habits are one of the factors that influence the development of gastric cancer and, although it has been seen that the Mediterranean diet has a protective effect on this type of cancer, there are different indexes to assess the degree of adherence to this dietary pattern; this implies differences in the results obtained in the reduction of risk. The aim of this work was to assess the effect of adherence to the Mediterranean diet, measured with five different indexes, on the risk of gastric cancer. ABSTRACT: The aim was to assess the effect of adherence to the Mediterranean Diet, measured with five different indexes, on the risk of gastric cancer. Data come from the multicase-control study MCC—Spain, which included 354 gastric cancer cases and 3040 controls with data on diet. We used five indexes to evaluate adherence to the Mediterranean diet and assess the association between each pattern with the risk of gastric cancer, using multivariate logistic regression. The analyses were performed for the whole set of gastric cancer cases, by anatomical location (cardia and non-cardia) and by histological type (intestinal and diffuse). According to the used index, a high adherence protects one from gastric cancer (between 48% (aOR = 0.52; CI 95% = 0.28–0.94) and 75% (aOR = 0.25; CI 95% = 0.12–0.52)), from non-cardia (between 48% (aOR = 0.52; CI 95% = 0.36–0.75) and 65% (aOR = 0.35; CI 95% = 0.23–0.52)), and from the intestinal type (between 41% (aOR = 0.59; CI 95% = 0.36–0.95) and 72% (aOR = 0.28; CI 95% = 0.16–0.50)), but not from the diffuse type. In conclusion, high adherence to a Mediterranean diet pattern is a protective factor for the risk of gastric cancer, with greater adherence leading to greater protection. |
format | Online Article Text |
id | pubmed-8582518 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85825182021-11-12 Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study Álvarez-Álvarez, Laura Vitelli-Storelli, Facundo Rubín-García, María Aragonés, Nuria Ardanaz, Eva Castaño-Vinyals, Gemma Obón-Santacana, Mireia Dierssen-Sotos, Trinidad Salas-Trejo, Dolores Tardón, Adonina Moleón, José Juan Jiménez Alguacil, Juan Chirlaque, María Dolores Pérez-Gómez, Beatriz Pollán, Marina Kogevinas, Manolis Martín, Vicente Cancers (Basel) Article SIMPLE SUMMARY: Dietary habits are one of the factors that influence the development of gastric cancer and, although it has been seen that the Mediterranean diet has a protective effect on this type of cancer, there are different indexes to assess the degree of adherence to this dietary pattern; this implies differences in the results obtained in the reduction of risk. The aim of this work was to assess the effect of adherence to the Mediterranean diet, measured with five different indexes, on the risk of gastric cancer. ABSTRACT: The aim was to assess the effect of adherence to the Mediterranean Diet, measured with five different indexes, on the risk of gastric cancer. Data come from the multicase-control study MCC—Spain, which included 354 gastric cancer cases and 3040 controls with data on diet. We used five indexes to evaluate adherence to the Mediterranean diet and assess the association between each pattern with the risk of gastric cancer, using multivariate logistic regression. The analyses were performed for the whole set of gastric cancer cases, by anatomical location (cardia and non-cardia) and by histological type (intestinal and diffuse). According to the used index, a high adherence protects one from gastric cancer (between 48% (aOR = 0.52; CI 95% = 0.28–0.94) and 75% (aOR = 0.25; CI 95% = 0.12–0.52)), from non-cardia (between 48% (aOR = 0.52; CI 95% = 0.36–0.75) and 65% (aOR = 0.35; CI 95% = 0.23–0.52)), and from the intestinal type (between 41% (aOR = 0.59; CI 95% = 0.36–0.95) and 72% (aOR = 0.28; CI 95% = 0.16–0.50)), but not from the diffuse type. In conclusion, high adherence to a Mediterranean diet pattern is a protective factor for the risk of gastric cancer, with greater adherence leading to greater protection. MDPI 2021-10-21 /pmc/articles/PMC8582518/ /pubmed/34771444 http://dx.doi.org/10.3390/cancers13215281 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Álvarez-Álvarez, Laura Vitelli-Storelli, Facundo Rubín-García, María Aragonés, Nuria Ardanaz, Eva Castaño-Vinyals, Gemma Obón-Santacana, Mireia Dierssen-Sotos, Trinidad Salas-Trejo, Dolores Tardón, Adonina Moleón, José Juan Jiménez Alguacil, Juan Chirlaque, María Dolores Pérez-Gómez, Beatriz Pollán, Marina Kogevinas, Manolis Martín, Vicente Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
title | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
title_full | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
title_fullStr | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
title_full_unstemmed | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
title_short | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
title_sort | relationship between the risk of gastric cancer and adherence to the mediterranean diet according to different estimators. mcc—spain study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582518/ https://www.ncbi.nlm.nih.gov/pubmed/34771444 http://dx.doi.org/10.3390/cancers13215281 |
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