Tonsillar Cancer with High CD8(+) T-Cell Infiltration Features Increased Levels of Dendritic Cells and Transcriptional Regulation Associated with an Inflamed Tumor Microenvironment

SIMPLE SUMMARY: Human papilloma virus (HPV) infection is the leading cause of tonsillar cancer (TC), and HPV(+) TC has a favorable prognosis as compared to HPV(−) TC. Further, high levels of CD8(+) T-cells in TC are associated with a favorable prognosis. Increased understanding of the tumor immune m...

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Autores principales: Jimenez, David Gomez, Sobti, Aastha, Askmyr, David, Sakellariou, Christina, Santos, Sofia Carreira, Swoboda, Sabine, Forslund, Ola, Greiff, Lennart, Lindstedt, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582523/
https://www.ncbi.nlm.nih.gov/pubmed/34771506
http://dx.doi.org/10.3390/cancers13215341

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