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Response to FEC Chemotherapy and Oncolytic HSV-1 Is Associated with Macrophage Polarization and Increased Expression of S100A8/A9 in Triple Negative Breast Cancer

SIMPLE SUMMARY: We have previously reported that a combination of clinical chemotherapies and oncolytic HSV-1 works to sensitize tumors to respond to immune checkpoint blockade. We further showed that this therapeutic platform worked via the upregulation of B cells and the concomitant control of imm...

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Detalles Bibliográficos
Autores principales: Vito, Alyssa, El-Sayes, Nader, Salem, Omar, Wan, Yonghong, Mossman, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582648/
https://www.ncbi.nlm.nih.gov/pubmed/34771752
http://dx.doi.org/10.3390/cancers13215590