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The Function of the Kynurenine Pathway in the Placenta: A Novel Pharmacotherapeutic Target?

(L-)tryptophan is metabolized via the kynurenine pathway into several kynurenine metabolites with distinct functions. Dysfunction of the kynurenine pathway can lead to impairments in vascular regulation, immune regulation, and tolerance. The first and rate limiting enzyme of this pathway, indoleamin...

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Detalles Bibliográficos
Autores principales:	Broekhuizen, Michelle, Danser, A. H. Jan, Reiss, Irwin K. M., Merkus, Daphne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582682/ https://www.ncbi.nlm.nih.gov/pubmed/34770059 http://dx.doi.org/10.3390/ijerph182111545

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