Cargando…

A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa

Despite making significant progress in tackling its HIV epidemic, South Africa, with 7.7 million people living with HIV, still has the biggest HIV epidemic in the world. The Government, in collaboration with developmental partners and agencies, has been strengthening its responses to the HIV epidemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayalew, Kassahun Abere, Manda, Samuel, Cai, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582764/
https://www.ncbi.nlm.nih.gov/pubmed/34769735
http://dx.doi.org/10.3390/ijerph182111215
_version_ 1784597059704193024
author Ayalew, Kassahun Abere
Manda, Samuel
Cai, Bo
author_facet Ayalew, Kassahun Abere
Manda, Samuel
Cai, Bo
author_sort Ayalew, Kassahun Abere
collection PubMed
description Despite making significant progress in tackling its HIV epidemic, South Africa, with 7.7 million people living with HIV, still has the biggest HIV epidemic in the world. The Government, in collaboration with developmental partners and agencies, has been strengthening its responses to the HIV epidemic to better target the delivery of HIV care, treatment strategies and prevention services. Population-based household HIV surveys have, over time, contributed to the country’s efforts in monitoring and understanding the magnitude and heterogeneity of the HIV epidemic. Local-level monitoring of progress made against HIV and AIDS is increasingly needed for decision making. Previous studies have provided evidence of substantial subnational variation in the HIV epidemic. Using HIV prevalence data from the 2016 South African Demographic and Health Survey, we compare three spatial smoothing models, namely, the intrinsically conditionally autoregressive normal, Laplace and skew-t (ICAR-normal, ICAR-Laplace and ICAR-skew-t) in the estimation of the HIV prevalence across 52 districts in South Africa. The parameters of the resulting models are estimated using Bayesian approaches. The skewness parameter for the ICAR-skew-t model was not statistically significant, suggesting the absence of skewness in the HIV prevalence data. Based on the deviance information criterion (DIC) model selection, the ICAR-normal and ICAR-Laplace had DIC values of 291.3 and 315, respectively, which were lower than that of the ICAR-skewed t (348.1). However, based on the model adequacy criterion using the conditional predictive ordinates (CPO), the ICAR-skew-t distribution had the lowest CPO value. Thus, the ICAR-skew-t was the best spatial smoothing model for the estimation of HIV prevalence in our study.
format Online
Article
Text
id pubmed-8582764
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-85827642021-11-12 A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa Ayalew, Kassahun Abere Manda, Samuel Cai, Bo Int J Environ Res Public Health Article Despite making significant progress in tackling its HIV epidemic, South Africa, with 7.7 million people living with HIV, still has the biggest HIV epidemic in the world. The Government, in collaboration with developmental partners and agencies, has been strengthening its responses to the HIV epidemic to better target the delivery of HIV care, treatment strategies and prevention services. Population-based household HIV surveys have, over time, contributed to the country’s efforts in monitoring and understanding the magnitude and heterogeneity of the HIV epidemic. Local-level monitoring of progress made against HIV and AIDS is increasingly needed for decision making. Previous studies have provided evidence of substantial subnational variation in the HIV epidemic. Using HIV prevalence data from the 2016 South African Demographic and Health Survey, we compare three spatial smoothing models, namely, the intrinsically conditionally autoregressive normal, Laplace and skew-t (ICAR-normal, ICAR-Laplace and ICAR-skew-t) in the estimation of the HIV prevalence across 52 districts in South Africa. The parameters of the resulting models are estimated using Bayesian approaches. The skewness parameter for the ICAR-skew-t model was not statistically significant, suggesting the absence of skewness in the HIV prevalence data. Based on the deviance information criterion (DIC) model selection, the ICAR-normal and ICAR-Laplace had DIC values of 291.3 and 315, respectively, which were lower than that of the ICAR-skewed t (348.1). However, based on the model adequacy criterion using the conditional predictive ordinates (CPO), the ICAR-skew-t distribution had the lowest CPO value. Thus, the ICAR-skew-t was the best spatial smoothing model for the estimation of HIV prevalence in our study. MDPI 2021-10-26 /pmc/articles/PMC8582764/ /pubmed/34769735 http://dx.doi.org/10.3390/ijerph182111215 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ayalew, Kassahun Abere
Manda, Samuel
Cai, Bo
A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa
title A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa
title_full A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa
title_fullStr A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa
title_full_unstemmed A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa
title_short A Comparison of Bayesian Spatial Models for HIV Mapping in South Africa
title_sort comparison of bayesian spatial models for hiv mapping in south africa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582764/
https://www.ncbi.nlm.nih.gov/pubmed/34769735
http://dx.doi.org/10.3390/ijerph182111215
work_keys_str_mv AT ayalewkassahunabere acomparisonofbayesianspatialmodelsforhivmappinginsouthafrica
AT mandasamuel acomparisonofbayesianspatialmodelsforhivmappinginsouthafrica
AT caibo acomparisonofbayesianspatialmodelsforhivmappinginsouthafrica
AT ayalewkassahunabere comparisonofbayesianspatialmodelsforhivmappinginsouthafrica
AT mandasamuel comparisonofbayesianspatialmodelsforhivmappinginsouthafrica
AT caibo comparisonofbayesianspatialmodelsforhivmappinginsouthafrica