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Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities
Healthcare-associated infections (HAIs) contribute to patient morbidity and mortality with an estimated 1.7 million infections and 99,000 deaths costing USD $28–34 billion annually in the United States alone. There is little understanding as to if current environmental surface disinfection practices...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582915/ https://www.ncbi.nlm.nih.gov/pubmed/34769620 http://dx.doi.org/10.3390/ijerph182111100 |
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author | Christenson, Elizabeth C. Cronk, Ryan Atkinson, Helen Bhatt, Aayush Berdiel, Emilio Cawley, Michelle Cho, Grace Coleman, Collin Knox Harrington, Cailee Heilferty, Kylie Fejfar, Don Grant, Emily J. Grigg, Karen Joshi, Tanmay Mohan, Suniti Pelak, Grace Shu, Yuhong Bartram, Jamie |
author_facet | Christenson, Elizabeth C. Cronk, Ryan Atkinson, Helen Bhatt, Aayush Berdiel, Emilio Cawley, Michelle Cho, Grace Coleman, Collin Knox Harrington, Cailee Heilferty, Kylie Fejfar, Don Grant, Emily J. Grigg, Karen Joshi, Tanmay Mohan, Suniti Pelak, Grace Shu, Yuhong Bartram, Jamie |
author_sort | Christenson, Elizabeth C. |
collection | PubMed |
description | Healthcare-associated infections (HAIs) contribute to patient morbidity and mortality with an estimated 1.7 million infections and 99,000 deaths costing USD $28–34 billion annually in the United States alone. There is little understanding as to if current environmental surface disinfection practices reduce pathogen load, and subsequently HAIs, in critical care settings. This evidence map includes a systematic review on the efficacy of disinfecting environmental surfaces in healthcare facilities. We screened 17,064 abstracts, 635 full texts, and included 181 articles for data extraction and study quality assessment. We reviewed ten disinfectant types and compared disinfectants with respect to study design, outcome organism, and fourteen indictors of study quality. We found important areas for improvement and gaps in the research related to study design, implementation, and analysis. Implementation of disinfection, a determinant of disinfection outcomes, was not measured in most studies and few studies assessed fungi or viruses. Assessing and comparing disinfection efficacy was impeded by study heterogeneity; however, we catalogued the outcomes and results for each disinfection type. We concluded that guidelines for disinfectant use are primarily based on laboratory data rather than a systematic review of in situ disinfection efficacy. It is critically important for practitioners and researchers to consider system-level efficacy and not just the efficacy of the disinfectant. |
format | Online Article Text |
id | pubmed-8582915 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85829152021-11-12 Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities Christenson, Elizabeth C. Cronk, Ryan Atkinson, Helen Bhatt, Aayush Berdiel, Emilio Cawley, Michelle Cho, Grace Coleman, Collin Knox Harrington, Cailee Heilferty, Kylie Fejfar, Don Grant, Emily J. Grigg, Karen Joshi, Tanmay Mohan, Suniti Pelak, Grace Shu, Yuhong Bartram, Jamie Int J Environ Res Public Health Systematic Review Healthcare-associated infections (HAIs) contribute to patient morbidity and mortality with an estimated 1.7 million infections and 99,000 deaths costing USD $28–34 billion annually in the United States alone. There is little understanding as to if current environmental surface disinfection practices reduce pathogen load, and subsequently HAIs, in critical care settings. This evidence map includes a systematic review on the efficacy of disinfecting environmental surfaces in healthcare facilities. We screened 17,064 abstracts, 635 full texts, and included 181 articles for data extraction and study quality assessment. We reviewed ten disinfectant types and compared disinfectants with respect to study design, outcome organism, and fourteen indictors of study quality. We found important areas for improvement and gaps in the research related to study design, implementation, and analysis. Implementation of disinfection, a determinant of disinfection outcomes, was not measured in most studies and few studies assessed fungi or viruses. Assessing and comparing disinfection efficacy was impeded by study heterogeneity; however, we catalogued the outcomes and results for each disinfection type. We concluded that guidelines for disinfectant use are primarily based on laboratory data rather than a systematic review of in situ disinfection efficacy. It is critically important for practitioners and researchers to consider system-level efficacy and not just the efficacy of the disinfectant. MDPI 2021-10-22 /pmc/articles/PMC8582915/ /pubmed/34769620 http://dx.doi.org/10.3390/ijerph182111100 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Christenson, Elizabeth C. Cronk, Ryan Atkinson, Helen Bhatt, Aayush Berdiel, Emilio Cawley, Michelle Cho, Grace Coleman, Collin Knox Harrington, Cailee Heilferty, Kylie Fejfar, Don Grant, Emily J. Grigg, Karen Joshi, Tanmay Mohan, Suniti Pelak, Grace Shu, Yuhong Bartram, Jamie Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities |
title | Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities |
title_full | Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities |
title_fullStr | Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities |
title_full_unstemmed | Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities |
title_short | Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities |
title_sort | evidence map and systematic review of disinfection efficacy on environmental surfaces in healthcare facilities |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582915/ https://www.ncbi.nlm.nih.gov/pubmed/34769620 http://dx.doi.org/10.3390/ijerph182111100 |
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