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CD8+ T Lymphocytes Immune Depletion and LAG-3 Overexpression in Hodgkin Lymphoma Tumor Microenvironment Exposed to Anti-PD-1 Immunotherapy

SIMPLE SUMMARY: Immune checkpoint blockers are important immunotherapies for the treatment of patients with Hodgkin lymphoma. The resistance mechanisms of these immunotherapies remain unknown. This pilot study aims to decipher the resistance mechanisms of immunotherapies in Hodgkin lymphoma. The mai...

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Detalles Bibliográficos
Autores principales: Michot, Jean-Marie, Mouraud, Severine, Adam, Julien, Lazarovici, Julien, Bigenwald, Camille, Rigaud, Charlotte, Tselikas, Lambros, Dartigues, Peggy, Danu, Alina, Bigorgne, Amélie, Minard, Veronique, Ghez, David, Marabelle, Aurélien, Zitvogel, Laurence, Ribrag, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582920/
https://www.ncbi.nlm.nih.gov/pubmed/34771650
http://dx.doi.org/10.3390/cancers13215487