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Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies

Molar-incisor hypomineralization (MIH) is a condition with specific clinical presentation whose etiology to date still remains unknown. This study prospectively investigated the association between nutrition during the 1st year of life and the presence of MIH in the permanent dentition. Data from 10...

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Autores principales: Khazaei, Yeganeh, Harris, Carla P., Heinrich, Joachim, Standl, Marie, Kühnisch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583051/
https://www.ncbi.nlm.nih.gov/pubmed/34769928
http://dx.doi.org/10.3390/ijerph182111411
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author Khazaei, Yeganeh
Harris, Carla P.
Heinrich, Joachim
Standl, Marie
Kühnisch, Jan
author_facet Khazaei, Yeganeh
Harris, Carla P.
Heinrich, Joachim
Standl, Marie
Kühnisch, Jan
author_sort Khazaei, Yeganeh
collection PubMed
description Molar-incisor hypomineralization (MIH) is a condition with specific clinical presentation whose etiology to date still remains unknown. This study prospectively investigated the association between nutrition during the 1st year of life and the presence of MIH in the permanent dentition. Data from 1070 10-year-old children from two prospective birth cohort studies were included. Information on exclusive breastfeeding (EBF) and introduction of 48 food items into the child’s diet was assessed at 4-, 6-, and 12-month time-points. Food diversity was defined according to the number of food items or food groups introduced into the child’s diet and then subsequent categorization into low-, middle- and high-diversity groups was performed. MIH was scored in the permanent dentition at age of 10 years. The statistical analysis included logistic and Poisson hurdle regression models adjusted for potential confounders. EBF, food item and food group diversity at 4-, 6-, 12-month time-points were found to be non-significant in most of the categories for the development of MIH. However, significantly higher odds for the presence of MIH were found for certain categories. Despite the limitation of this study, such as arbitrary cut-offs for categorization of food items, the results of this study suggest the lack of an association between early nutrition in the first year of life and MIH in the permanent dentition.
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spelling pubmed-85830512021-11-12 Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies Khazaei, Yeganeh Harris, Carla P. Heinrich, Joachim Standl, Marie Kühnisch, Jan Int J Environ Res Public Health Article Molar-incisor hypomineralization (MIH) is a condition with specific clinical presentation whose etiology to date still remains unknown. This study prospectively investigated the association between nutrition during the 1st year of life and the presence of MIH in the permanent dentition. Data from 1070 10-year-old children from two prospective birth cohort studies were included. Information on exclusive breastfeeding (EBF) and introduction of 48 food items into the child’s diet was assessed at 4-, 6-, and 12-month time-points. Food diversity was defined according to the number of food items or food groups introduced into the child’s diet and then subsequent categorization into low-, middle- and high-diversity groups was performed. MIH was scored in the permanent dentition at age of 10 years. The statistical analysis included logistic and Poisson hurdle regression models adjusted for potential confounders. EBF, food item and food group diversity at 4-, 6-, 12-month time-points were found to be non-significant in most of the categories for the development of MIH. However, significantly higher odds for the presence of MIH were found for certain categories. Despite the limitation of this study, such as arbitrary cut-offs for categorization of food items, the results of this study suggest the lack of an association between early nutrition in the first year of life and MIH in the permanent dentition. MDPI 2021-10-29 /pmc/articles/PMC8583051/ /pubmed/34769928 http://dx.doi.org/10.3390/ijerph182111411 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Khazaei, Yeganeh
Harris, Carla P.
Heinrich, Joachim
Standl, Marie
Kühnisch, Jan
Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_full Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_fullStr Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_full_unstemmed Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_short Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_sort association study on nutrition in the first year of life and molar-incisor hypomineralization (mih)—results from the giniplus and lisa birth cohort studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583051/
https://www.ncbi.nlm.nih.gov/pubmed/34769928
http://dx.doi.org/10.3390/ijerph182111411
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