Hepatocarcinogenesis Prevention by Pirfenidone Is PPARγ Mediated and Involves Modification of Nuclear NF-kB p65/p50 Ratio

Targeted therapies for regulating processes such as inflammation, apoptosis, and fibrogenesis might modulate human HCC development. Pirfenidone (PFD) has shown anti-fibrotic and anti-inflammatory functions in both clinical and experimental studies. The aim of this study was to evaluate PPARγ express...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva-Gomez, Jorge Antonio, Galicia-Moreno, Marina, Sandoval-Rodriguez, Ana, Miranda-Roblero, Hipolito Otoniel, Lucano-Landeros, Silvia, Santos, Arturo, Monroy-Ramirez, Hugo Christian, Armendariz-Borunda, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583060/
https://www.ncbi.nlm.nih.gov/pubmed/34768791
http://dx.doi.org/10.3390/ijms222111360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583060/
https://www.ncbi.nlm.nih.gov/pubmed/34768791
http://dx.doi.org/10.3390/ijms222111360

Ejemplares similares